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Selective tumor killing based on specific DNA-damage response deficiencies

Organisms constantly undergo various stresses within their life span, which can damage their DNA. In order to maintain genomic stability and counteract the development of unwanted genomic mutations, organisms have evolved a DNA-damage response (DDR) to protect their genome. Due to the critical roles...

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Detalhes bibliográficos
Main Authors: Biss, Michael, Xiao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367714/
https://ncbi.nlm.nih.gov/pubmed/22258411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.13.5.18921
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