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DNA mismatch repair proficiency executing 5-fluorouracil cytotoxicity in colorectal cancer cells
BACKGROUND: 5-fluorouracil (5-FU)-based chemotherapy is the standard treatment for advanced stage colorectal cancer (CRC) patients. Several groups including ours have reported that stage II-III colorectal cancer patients whose tumors retain DNA Mismatch repair (MMR) function derive a benefit from 5-...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367669/ https://ncbi.nlm.nih.gov/pubmed/21814034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.8.17169 |
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