Severe Developmental B Lymphopoietic Defects in Foxp3-Deficient Mice are Refractory to Adoptive Regulatory T Cell Therapy

The role of Foxp3-expressing regulatory T (T(reg)) cells in tolerance and autoimmunity is well-established. However, although of considerable clinical interest, the role of T(reg) cells in the regulation of hematopoietic homeostasis remains poorly understood. Thus, we analysed B and T lymphopoiesis...

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Detalhes bibliográficos
Main Authors: Riewaldt, Julia, Düber, Sandra, Boernert, Marie, Krey, Martina, Dembinski, Marcin, Weiss, Siegfried, Garbe, Annette I., Kretschmer, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367401/
https://ncbi.nlm.nih.gov/pubmed/22679447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00141
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