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Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation
Under physiological conditions, CD4(+) regulatory T (Treg) cells expressing the transcription factor Foxp3 are generated in the thymus [thymus-derived Foxp3(+) Treg (tTregs) cells] and extrathymically at peripheral sites [peripherally induced Foxp3(+) Treg (pTreg) cell], and both developmental subse...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801288/ https://ncbi.nlm.nih.gov/pubmed/29456534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00125 |
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