Ferroptosis: An Iron-Dependent Form of Non-Apoptotic Cell Death

Non-apoptotic forms of cell death may facilitate the selective elimination of some tumor cells or be activated in specific pathological states. The oncogenic RAS-selective lethal small molecule erastin triggers a unique iron-dependent form of non-apoptotic cell death that we term ferroptosis. Ferrop...

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Detalles Bibliográficos
Autores principales: Dixon, Scott J., Lemberg, Kathryn M., Lamprecht, Michael R., Skouta, Rachid, Zaitsev, Eleina M., Gleason, Caroline E., Patel, Darpan N., Bauer, Andras J., Cantley, Alexandra M., Yang, Wan Seok, Morrison, Barclay, Stockwell, Brent R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367386/
https://ncbi.nlm.nih.gov/pubmed/22632970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.042
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