Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices()

We introduce a label-free approach for sensing polymerase reactions on deoxyribonucleic acid (DNA) using a chelator-modified silicon-on-insulator field-effect transistor (SOI-FET) that exhibits selective and reversible electrical response to pyrophosphate anions. The chemical modification of the sen...

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Bibliografiske detaljer
Main Authors: Credo, Grace M., Su, Xing, Wu, Kai, Elibol, Oguz H., Liu, David J., Reddy, Bobby, Tsai, Ta-Wei, Dorvel, Brian R., Daniels, Jonathan S., Bashir, Rashid, Varma, Madoo
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367324/
https://ncbi.nlm.nih.gov/pubmed/22262038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2an15930a
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