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Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices()
We introduce a label-free approach for sensing polymerase reactions on deoxyribonucleic acid (DNA) using a chelator-modified silicon-on-insulator field-effect transistor (SOI-FET) that exhibits selective and reversible electrical response to pyrophosphate anions. The chemical modification of the sen...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367324/ https://ncbi.nlm.nih.gov/pubmed/22262038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2an15930a |
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