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Effect of Glycocalyx on Drug Delivery Carriers Targeted to Endothelial Cells

Animal models have shown that coupling ligands, targeted to endothelium surface receptors, with drug delivery carriers (DDC) can optimize the treatment of diseases by specific vascular delivery. The endothelium is exposed to hydrodynamic forces that modulate the expression of these cellular adhesion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Calderon, Andres J., Baig, Madiha, Pichette, Ben, Muzykantov, Vladimir, Muro, Silvia, Eckmann, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367256/
https://ncbi.nlm.nih.gov/pubmed/22679359
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