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Delivering minocycline into brain endothelial cells with liposome-based technology
Minocycline has been proposed as a way to blunt neurovascular injury from matrix metalloproteinases (MMPs) during stroke. However, recent clinical trials suggest that high levels of minocycline may have deleterious side-effects. Here, we showed that very high minocycline concentrations damage endoth...
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| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367232/ https://ncbi.nlm.nih.gov/pubmed/22491155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.48 |
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