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Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae
In eukaryotic cells, ribosomal DNA (rDNA) forms the basis of the nucleolus. In Saccharomyces cerevisiae, 100–200 copies of a 9.1-kb rDNA repeat exist as a tandem array on chromosome XII. The stability of this highly repetitive array is maintained through silencing. However, the precise mechanisms th...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367210/ https://ncbi.nlm.nih.gov/pubmed/22362748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks188 |
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