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Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome

Dot1 is a conserved histone methyltransferase that methylates histone H3 on lysine 79. We previously observed that in Saccharomyces cerevisiae, a single DOT1 gene encodes two Dot1 protein species. Here, we show that the relative abundance of the two isoforms changed under nutrient-limiting condition...

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Detalhes bibliográficos
Main Authors: Frederiks, Floor, Heynen, Guus J. J. E., van Deventer, Sjoerd J., Janssen, Hans, van Leeuwen, Fred
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790890/
https://ncbi.nlm.nih.gov/pubmed/19778927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp765
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