Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae

In eukaryotic cells, ribosomal DNA (rDNA) forms the basis of the nucleolus. In Saccharomyces cerevisiae, 100–200 copies of a 9.1-kb rDNA repeat exist as a tandem array on chromosome XII. The stability of this highly repetitive array is maintained through silencing. However, the precise mechanisms th...

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Bibliografiske detaljer
Main Authors: Ha, Cheol Woong, Sung, Min-Kyung, Huh, Won-Ki
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367210/
https://ncbi.nlm.nih.gov/pubmed/22362748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks188
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