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Chemical and biological approaches to improve the efficiency of homologous recombination in human cells mediated by artificial restriction DNA cutter

A chemistry-based artificial restriction DNA cutter (ARCUT) was recently prepared from Ce(IV)/EDTA complex and a pair of pseudo-complementary peptide nucleic acids. This cutter has freely tunable scission-site and site specificity. In this article, homologous recombination (HR) in human cells was pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Katada, Hitoshi, Harumoto, Toshimasa, Shigi, Narumi, Komiyama, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367209/
https://ncbi.nlm.nih.gov/pubmed/22362741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks185
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