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Chemical modifications of artificial restriction DNA cutter (ARCUT) to promote its in vivo and in vitro applications
Recently, completely chemistry-based tools for site-selective scission of DNA (ARCUT) have been prepared by combining 2 strands of pseudo-complementary PNA (pcPNA: site-selective activator) and a Ce(IV)-EDTA complex (molecular scissors). Its site-specificity is sufficient to cut the whole human geno...
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| Publicado no: | Artif DNA PNA XNA |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5329899/ https://ncbi.nlm.nih.gov/pubmed/26744220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1949095X.2015.1112457 |
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