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Chemical modifications of artificial restriction DNA cutter (ARCUT) to promote its in vivo and in vitro applications

Recently, completely chemistry-based tools for site-selective scission of DNA (ARCUT) have been prepared by combining 2 strands of pseudo-complementary PNA (pcPNA: site-selective activator) and a Ce(IV)-EDTA complex (molecular scissors). Its site-specificity is sufficient to cut the whole human geno...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Artif DNA PNA XNA
मुख्य लेखक: Komiyama, Makoto
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329899/
https://ncbi.nlm.nih.gov/pubmed/26744220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1949095X.2015.1112457
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