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Inhibition of DNA polymerase alpha by aphidicolin derivatives.
17-Acetylaphidicolin was 10-fold weaker and two derivatives lacking hydroxyl groups at the 16 and 17 positions were 100-fold weaker than aphidicolin as inhibitors of DNA polymerase alpha from HeLa and Chinese hamster ovary cells. 17,18-Diacetyl, 3,17,18-triacetyl and 3-epi derivatives of aphidicolin...
Sparad:
| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1988
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC336720/ https://ncbi.nlm.nih.gov/pubmed/3133639 |
| Taggar: |
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