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Inhibition of DNA polymerase alpha by aphidicolin derivatives.

17-Acetylaphidicolin was 10-fold weaker and two derivatives lacking hydroxyl groups at the 16 and 17 positions were 100-fold weaker than aphidicolin as inhibitors of DNA polymerase alpha from HeLa and Chinese hamster ovary cells. 17,18-Diacetyl, 3,17,18-triacetyl and 3-epi derivatives of aphidicolin...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Arabshahi, L, Brown, N, Khan, N, Wright, G
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1988
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3133639/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.11.5107
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