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Inhibition of DNA polymerase alpha by aphidicolin derivatives.

17-Acetylaphidicolin was 10-fold weaker and two derivatives lacking hydroxyl groups at the 16 and 17 positions were 100-fold weaker than aphidicolin as inhibitors of DNA polymerase alpha from HeLa and Chinese hamster ovary cells. 17,18-Diacetyl, 3,17,18-triacetyl and 3-epi derivatives of aphidicolin...

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Bibliografski detalji
Glavni autori: Arabshahi, L, Brown, N, Khan, N, Wright, G
Format: Artigo
Jezik:Inglês
Izdano: 1988
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC336720/
https://ncbi.nlm.nih.gov/pubmed/3133639
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