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The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice

We have previously shown that β-endorphin plays a functional role in the rewarding effect of acute cocaine. Considering that β-endorphin has high affinity for the μ opioid receptor, we determined the role of this receptor in the rewarding action of acute cocaine. For comparison, we assessed the role...

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Hlavní autoři: Nguyen, Alexander T., Marquez, Paul, Hamid, Abdul, Kieffer, Brigitte, Friedman, Theodore C., Lutfy, Kabirullah
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367137/
https://ncbi.nlm.nih.gov/pubmed/22575525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.04.040
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