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The role of the ORL1 receptor in motor stimulatory and rewarding actions of buprenorphine and morphine
We have previously shown that the ability of buprenorphine to activate the opioid receptor-like (ORL1) receptor compromises its antinociceptive effect. Furthermore, morphine has been shown to alter the level of orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the ORL1 receptor, raising the p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631239/ https://ncbi.nlm.nih.gov/pubmed/18634857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.06.027 |
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