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The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine

Previous studies have shown that orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the opioid receptor-like (ORL-1) receptor, reduces the rewarding and addictive properties of cocaine and other drugs of abuse. In the present study, using the conditioned place preference (CPP) paradigm, as an...

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Detalhes bibliográficos
Main Authors: Marquez, Paul, Nguyen, Alexander T., Hamid, Abdul, Lutfy, Kabirullah
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276976/
https://ncbi.nlm.nih.gov/pubmed/18082848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.11.003
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