Llwytho...

Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice

Spinal GABA(A) receptor modulation with agonists and allosteric modulators evokes analgesia and antinociception. Changes in KCC2 expression or function that occur after peripheral nerve injury can result in an impairment in the Cl(−) extrusion capacity of spinal dorsal horn neurons. This, in turn, a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Asiedu, M. N., Mejia, G., Ossipov, M. K., Malan, T. P., Kaila, K., Price, T. J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367103/
https://ncbi.nlm.nih.gov/pubmed/22537560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2012.03.002
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