Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion

MMP-9 deficiency protected against photochemical thrombosis induced brain hemorrhagic transformation (HT), but it did not protect against tissue plasminogen activator induced brain hemorrhage. The roles of MMP-2 and/or MMP-9 knockout (KO) in mechanical reperfusion induced HT after ischemia have not...

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Bibliographic Details
Main Authors: Suofu, Yalikun, Clark, Joseph F., Broderick, Joseph P., Kurosawa, Yuko, Wagner, Kenneth R., Lu, Aigang
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367043/
https://ncbi.nlm.nih.gov/pubmed/22521821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.03.036
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