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Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1 hour of cerebral ischemia and 23 hours of reperfusion

Although elevated MMP-2 levels were highly related to the degradation of tight junction (TJ) proteins and basal lamina and neuronal injury after ischemia, until very recently, little experimental evidence was available to test the role of the MMP-2 knockout (KO) in blood-brain-barrier injury and dev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lu, Aigang, Suofu, Yalikun, Guan, Fanglin, Broderick, Joseph P., Wagner, Kenneth R., Clark, Joseph F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827875/
https://ncbi.nlm.nih.gov/pubmed/24035828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.08.068
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