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Aflatoxin-Induced TP53 R249S Mutation in HepatoCellular Carcinoma in Thailand: Association with Tumors Developing in the Absence of Liver Cirrhosis

Primary Liver Cancer (PLC) is the leading cause of death by cancer among males in Thailand and the 3(rd) among females. Most cases are hepatocellular carcinoma (HCC) but cholangiocarcinomas represent between 4 and 80% of liver cancers depending upon geographic area. Most HCC are associated with chro...

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Détails bibliographiques
Auteurs principaux: Villar, Stephanie, Ortiz-Cuaran, Sandra, Abedi-Ardekani, Behnoush, Gouas, Doriane, Nogueira da Costa, Andre, Plymoth, Amelie, Khuhaprema, Thiravud, Kalalak, Anant, Sangrajrang, Suleeporn, Friesen, Marlin D., Groopman, John D., Hainaut, Pierre
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366967/
https://ncbi.nlm.nih.gov/pubmed/22675488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037707
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