Prevalence of Aflatoxin-associated TP53R249S Mutation in Hepatocellular Carcinoma in Hispanics in South Texas

We aimed to determine whether aflatoxin dietary exposure plays a role in the high incidence of hepatocellular carcinoma (HCC) observed among Hispanics in South Texas. We measured TP53R249S somatic mutation, hallmark of aflatoxin etiology in HCC, using droplet digital PCR and restriction fragment len...

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Veröffentlicht in:Cancer Prev Res (Phila)
Hauptverfasser: Jiao, Jingjing, Niu, Weibo, Wang, Ying, Baggerly, Keith, Ye, Yuanqing, Wu, Xifeng, Davenport, Dewitt, Almeda, Jose Luis, Betancourt-Garcia, Monica M., Forse, R. Armour, Stevenson, Heather L., Watt, Gordon P., McCormick, Joseph B, Fisher-Hoch, Susan P., Beretta, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811406/
https://ncbi.nlm.nih.gov/pubmed/29089331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0235
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