TP53 R249S mutation, genetic variations in HBX and risk of hepatocellular carcinoma in The Gambia

In regions with high prevalence of chronic hepatitis B virus (HBV) infection and dietary aflatoxin B(1) (AFB(1)) exposure, hepatocellular carcinomas (HCCs) often contain TP53 mutation at codon 249 (R249S). Furthermore, a C-terminal truncated HBx protein expressed from hepatocyte integrated HBV is as...

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Detalhes bibliográficos
Main Authors: Gouas, Doriane A., Villar, Stéphanie, Ortiz-Cuaran, Sandra, Legros, Pénélope, Ferro, Gilles, Kirk, Gregory D., Lesi, Olufunmilayo A., Mendy, Maimuna, Bah, Ebrima, Friesen, Marlin D., Groopman, John, Chemin, Isabelle, Hainaut, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388490/
https://ncbi.nlm.nih.gov/pubmed/22759751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs135
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