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Nucleolin Inhibits G4 Oligonucleotide Unwinding by Werner Helicase

BACKGROUND: The Werner protein (WRNp), a member of the RecQ helicase family, is strongly associated with the nucleolus, as is nucleolin (NCL), an important nucleolar constituent protein. Both WRNp and NCL respond to the effects of DNA damaging agents. Therefore, we have investigated if these nuclear...

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Autors principals: Indig, Fred E., Rybanska, Ivana, Karmakar, Parimal, Devulapalli, Chakravarty, Fu, Haiqing, Carrier, France, Bohr, Vilhelm A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366963/
https://ncbi.nlm.nih.gov/pubmed/22675465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035229
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