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Arsenic Promotes Ubiquitinylation and Lysosomal Degradation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channels in Human Airway Epithelial Cells

Arsenic exposure significantly increases respiratory bacterial infections and reduces the ability of the innate immune system to eliminate bacterial infections. Recently, we observed in the gill of killifish, an environmental model organism, that arsenic exposure induced the ubiquitinylation and deg...

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Autors principals: Bomberger, Jennifer M., Coutermarsh, Bonita A., Barnaby, Roxanna L., Stanton, Bruce A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366821/
https://ncbi.nlm.nih.gov/pubmed/22467879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338855
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