Antigen-presenting cell–derived complement modulates graft-versus-host disease

Acute graft-versus-host disease (GvHD) is a serious complication of allogeneic hematopoietic cell transplantation (allo-HCT) that results from donor allogeneic T cell attack on host tissues. Based on previous work implicating immune cell–derived C3a and C5a as regulators of T cell immunity, we exami...

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Bibliografiske detaljer
Main Authors: Kwan, Wing-Hong, Hashimoto, Daigo, Paz-Artal, Estela, Ostrow, Katya, Greter, Melanie, Raedler, Hugo, Medof, M. Edward, Merad, Miriam, Heeger, Peter S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366405/
https://ncbi.nlm.nih.gov/pubmed/22585573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61019
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