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Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells
CD4(+)Foxp3(+) regulatory T cells (Treg) are critical regulators of immune homeostasis and self-tolerance. Whereas thymic-derived or natural Treg (nTreg) stably express Foxp3, adaptive or induced Treg (iTreg) generated from peripheral CD4 T cells are susceptible to inflammation-induced reversion to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679341/ https://ncbi.nlm.nih.gov/pubmed/23690475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300847 |
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