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Complement Regulates CD4 T-Cell Help to CD8 T Cells Required for Murine Allograft Rejection
Although induction of CD8 T-cell responses to transplants requires CD4-cell help, how this help is transmitted remains incompletely characterized. In vitro, cognate interactions between CD4 T cells and dendritic cells (DCs) induce C3a and C5a production. CD8(+) T cells lacking C3a receptor (C3aR) an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157191/ https://ncbi.nlm.nih.gov/pubmed/21704012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.038 |
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