Complement Regulates CD4 T-Cell Help to CD8 T Cells Required for Murine Allograft Rejection

Although induction of CD8 T-cell responses to transplants requires CD4-cell help, how this help is transmitted remains incompletely characterized. In vitro, cognate interactions between CD4 T cells and dendritic cells (DCs) induce C3a and C5a production. CD8(+) T cells lacking C3a receptor (C3aR) an...

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Detaylı Bibliyografya
Asıl Yazarlar: Vieyra, Mark, Leisman, Staci, Raedler, Hugo, Kwan, Wing-Hong, Yang, Min, Strainic, Michael G., Medof, M. Edward, Heeger, Peter S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2011
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157191/
https://ncbi.nlm.nih.gov/pubmed/21704012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.038
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