Genetic modifiers of hypertension in soluble guanylate cyclase α1–deficient mice

Nitric oxide (NO) plays an essential role in regulating hypertension and blood flow by inducing relaxation of vascular smooth muscle. Male mice deficient in a NO receptor component, the α1 subunit of soluble guanylate cyclase (sGCα(1)), are prone to hypertension in some, but not all, mouse strains,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Buys, Emmanuel S., Raher, Michael J., Kirby, Andrew, Mohd, Shahid, Baron, David M., Hayton, Sarah R., Tainsh, Laurel T., Sips, Patrick Y., Rauwerdink, Kristen M., Yan, Qingshang, Tainsh, Robert E.T., Shakartzi, Hannah R., Stevens, Christine, Decaluwé, Kelly, Rodrigues-Machado, Maria da Gloria, Malhotra, Rajeev, Van de Voorde, Johan, Wang, Tong, Brouckaert, Peter, Daly, Mark J., Bloch, Kenneth D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366402/
https://ncbi.nlm.nih.gov/pubmed/22565307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60119
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