Genetic modifiers of hypertension in soluble guanylate cyclase α1–deficient mice

Nitric oxide (NO) plays an essential role in regulating hypertension and blood flow by inducing relaxation of vascular smooth muscle. Male mice deficient in a NO receptor component, the α1 subunit of soluble guanylate cyclase (sGCα(1)), are prone to hypertension in some, but not all, mouse strains,...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Buys, Emmanuel S., Raher, Michael J., Kirby, Andrew, Mohd, Shahid, Baron, David M., Hayton, Sarah R., Tainsh, Laurel T., Sips, Patrick Y., Rauwerdink, Kristen M., Yan, Qingshang, Tainsh, Robert E.T., Shakartzi, Hannah R., Stevens, Christine, Decaluwé, Kelly, Rodrigues-Machado, Maria da Gloria, Malhotra, Rajeev, Van de Voorde, Johan, Wang, Tong, Brouckaert, Peter, Daly, Mark J., Bloch, Kenneth D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2012
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366402/
https://ncbi.nlm.nih.gov/pubmed/22565307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60119
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