CD19 is a major B cell receptor–independent activator of MYC-driven B-lymphomagenesis

PAX5, a B cell–specific transcription factor, is overexpressed through chromosomal translocations in a subset of B cell lymphomas. Previously, we had shown that activation of immunoreceptor tyrosine-based activation motif (ITAM) proteins and B cell receptor (BCR) signaling by PAX5 contributes to B-l...

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Bibliografiske detaljer
Main Authors: Chung, Elaine Y., Psathas, James N., Yu, Duonan, Li, Yimei, Weiss, Mitchell J., Thomas-Tikhonenko, Andrei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366393/
https://ncbi.nlm.nih.gov/pubmed/22546857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45851
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