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MYC and the Art of MicroRNA Maintenance

MYC is a noncanonical transcription factor that binds to thousands of genomic loci and affects >15% of the human transcriptome, with surprisingly little overlap between MYC-bound and -regulated genes. This discordance raises the question whether MYC chooses its targets based on their individual b...

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Библиографические подробности
Главные авторы: Psathas, James N., Thomas-Tikhonenko, Andrei
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109576/
https://ncbi.nlm.nih.gov/pubmed/24737842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014175
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