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Chromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications

Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical management of FA and often reveals cytogenetic aberrations. Here, we review bo...

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Detalles Bibliográficos
Main Authors: Meyer, Stefan, Neitzel, Heidemarie, Tönnies, Holger
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366199/
https://ncbi.nlm.nih.gov/pubmed/22675616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/349837
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