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Chromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications

Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical management of FA and often reveals cytogenetic aberrations. Here, we review bo...

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Detalhes bibliográficos
Main Authors: Meyer, Stefan, Neitzel, Heidemarie, Tönnies, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366199/
https://ncbi.nlm.nih.gov/pubmed/22675616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/349837
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