Extracellular matrix protein CCN1 limits oncolytic efficacy in glioma

Oncolytic viral therapy has been explored widely as an option for glioma treatment but its effectiveness has remained limited. CCN1 is an extracellular matrix (ECM) protein elevated in cancer cells that modulates their adhesion and migration by binding cell surface receptors. In this study, we exami...

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Bibliografiske detaljer
Main Authors: Haseley, Amy, Boone, Sean, Wojton, Jeffrey, Yu, Lianbo, Yoo, Ji Young, Yu, Jianhua, Kurozumi, Kazuhiko, Glorioso, Joseph C., Caligiuri, Michael A., Kaur, Balveen
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366191/
https://ncbi.nlm.nih.gov/pubmed/22282654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2526
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