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Extracellular matrix protein CCN1 limits oncolytic efficacy in glioma

Oncolytic viral therapy has been explored widely as an option for glioma treatment but its effectiveness has remained limited. CCN1 is an extracellular matrix (ECM) protein elevated in cancer cells that modulates their adhesion and migration by binding cell surface receptors. In this study, we exami...

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Hlavní autoři: Haseley, Amy, Boone, Sean, Wojton, Jeffrey, Yu, Lianbo, Yoo, Ji Young, Yu, Jianhua, Kurozumi, Kazuhiko, Glorioso, Joseph C., Caligiuri, Michael A., Kaur, Balveen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366191/
https://ncbi.nlm.nih.gov/pubmed/22282654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2526
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