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Increased α-synuclein phosphorylation and nitration in the aging primate substantia nigra

Post-translational modifications of α-synuclein occur in the brain of patients affected by Parkinson's disease and other α-synucleinopathies, as indicated by the accumulation of Lewy inclusions containing phosphorylated (at serine 129) and nitrated α-synuclein. Here we found that phospho-Ser 12...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McCormack, A L, Mak, S K, Di Monte, D A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366084/
https://ncbi.nlm.nih.gov/pubmed/22647852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.50
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