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A Stretch of Polybasic Residues Mediates Cdc42 GTPase-activating Protein (CdGAP) Binding to Phosphatidylinositol 3,4,5-Trisphosphate and Regulates Its GAP Activity
The Rho family of small GTPases are membrane-associated molecular switches involved in the control of a wide range of cellular activities, including cell migration, adhesion, and proliferation. Cdc42 GTPase-activating protein (CdGAP) is a phosphoprotein showing GAP activity toward Rac1 and Cdc42. Cd...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365996/ https://ncbi.nlm.nih.gov/pubmed/22518840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.344606 |
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