Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are characterized by their ability to produce high levels of type 1 interferons in response to ligands that activate TLR7 and TLR9, but the signaling pathways required for IFN production are incompletely understood. Here we exploit the human pDC cell line Gen2.2 a...

詳細記述

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書誌詳細
主要な著者: Pauls, Eduardo, Shpiro, Natalia, Peggie, Mark, Young, Erick R., Sorcek, Ronald J., Tan, Li, Choi, Hwan Geun, Cohen, Philip
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
Immunology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365954/
https://ncbi.nlm.nih.gov/pubmed/22511786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345405
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