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DNA Repair and Replication Fork Helicases Are Differentially Affected by Alkyl Phosphotriester Lesion
DNA helicases are directly responsible for catalytically unwinding duplex DNA in an ATP-dependent and directionally specific manner and play essential roles in cellular nucleic acid metabolism. It has been conventionally thought that DNA helicases are inhibited by bulky covalent DNA adducts in a str...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365951/ https://ncbi.nlm.nih.gov/pubmed/22500020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.352757 |
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