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Vacuolar H(+)-ATPase (V-ATPase) Promotes Vacuolar Membrane Permeabilization and Nonapoptotic Death in Stressed Yeast

Stress in the endoplasmic reticulum caused by tunicamycin, dithiothreitol, and azole-class antifungal drugs can induce nonapoptotic cell death in yeasts that can be blocked by the action of calcineurin (Cn), a Ca(2+)-dependent serine/threonine protein phosphatase. To identify additional factors that...

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Bibliographic Details
Main Authors: Kim, Hyemin, Kim, Adam, Cunningham, Kyle W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365936/
https://ncbi.nlm.nih.gov/pubmed/22511765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363390
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