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Loss of Vacuolar H(+)-ATPase (V-ATPase) Activity in Yeast Generates an Iron Deprivation Signal That Is Moderated by Induction of the Peroxiredoxin TSA2

Vacuolar H(+)-ATPases (V-ATPases) acidify intracellular organelles and help to regulate overall cellular pH. Yeast vma mutants lack V-ATPase activity and allow exploration of connections between cellular pH, iron, and redox homeostasis common to all eukaryotes. A previous microarray study in a vma m...

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Detalhes bibliográficos
Main Authors: Diab, Heba I., Kane, Patricia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630902/
https://ncbi.nlm.nih.gov/pubmed/23457300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419259
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