DiGeorge Syndrome Critical Region 8 (DGCR8) Protein-mediated microRNA Biogenesis Is Essential for Vascular Smooth Muscle Cell Development in Mice

DiGeorge Critical Region 8 (DGCR8) is a double-stranded RNA-binding protein that interacts with Drosha and facilitates microRNA (miRNA) maturation. However, the role of DGCR8 in vascular smooth muscle cells (VSMCs) is not well understood. To investigate whether DGCR8 contributes to miRNA maturation...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Zixuan, Wu, Jianmin, Yang, Chuanhe, Fan, Pei, Balazs, Louisa, Jiao, Yan, Lu, Meifeng, Gu, Weikuan, Li, Chengyao, Pfeffer, Lawrence M., Tigyi, Gabor, Yue, Junming
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365935/
https://ncbi.nlm.nih.gov/pubmed/22511778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351791
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