DiGeorge Syndrome Critical Region 8 (DGCR8) Protein-mediated microRNA Biogenesis Is Essential for Vascular Smooth Muscle Cell Development in Mice

Eitemau Tebyg

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• Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality
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• The Core Microprocessor Component DiGeorge Syndrome Critical Region 8 (DGCR8) Is a Nonspecific RNA-binding Protein
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• Microprocessor Complex Subunit DiGeorge Syndrome Critical Region Gene 8 (Dgcr8) Is Required for Schwann Cell Myelination and Myelin Maintenance
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• Physical mapping by FISH of the DiGeorge critical region (DGCR): Involvement of the region in familial cases
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