DiGeorge Syndrome Critical Region 8 (DGCR8) Protein-mediated microRNA Biogenesis Is Essential for Vascular Smooth Muscle Cell Development in Mice

DiGeorge Critical Region 8 (DGCR8) is a double-stranded RNA-binding protein that interacts with Drosha and facilitates microRNA (miRNA) maturation. However, the role of DGCR8 in vascular smooth muscle cells (VSMCs) is not well understood. To investigate whether DGCR8 contributes to miRNA maturation...

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Hlavní autoři: Chen, Zixuan, Wu, Jianmin, Yang, Chuanhe, Fan, Pei, Balazs, Louisa, Jiao, Yan, Lu, Meifeng, Gu, Weikuan, Li, Chengyao, Pfeffer, Lawrence M., Tigyi, Gabor, Yue, Junming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365935/
https://ncbi.nlm.nih.gov/pubmed/22511778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351791
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