Adoptive transfer of PR1 cytotoxic T lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model

BACKGROUND AIMS: Tumor antigen-specific cytotoxic T lymphocytes (CTL) have been used in the treatment of human cancer, including leukemia. Several studies have established PR1 peptide, an HLA-A2.1-restricted peptide derived from proteinase 3 (P3), as a human leukemia-associated antigen. PR1-specific...

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Hauptverfasser: Ma, Qing, Wang, Changqing, Jones, Dan, Quintanilla, Kathryn E., Li, Dan, Wang, Yang, Wieder, Eric D., Clise-Dwyer, Karen, Alatrash, Gheath, You, M. James, Munsell, Mark F., Lu, Sijie, Qazibash, Muzaffar H., Molldrem, Jeffrey J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365857/
https://ncbi.nlm.nih.gov/pubmed/20735170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2010.506506
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