Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma

Human aldo-keto reductase family 1 member C3 (AKR1C3) was initially identified as a critical enzyme in reducing 5α-dihydrotestosterone (5α-DHT) to 5α-androstane-3α,17β-diol (3α-diol) and oxidizing 3α-diol to androsterone. Based on these enzymatic activities, AKR1C3 was originally named type 2 3α-hyd...

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Bibliografiske detaljer
Main Authors: Miller, Valerie L, Lin, Hsueh-Kung, Murugan, Paari, Fan, Michael, Penning, Trevor M, Brame, Lacy S, Yang, Qing, Fung, Kar-Ming
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2012
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365826/
https://ncbi.nlm.nih.gov/pubmed/22670171
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